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Nutr Diabetes (2017) 7(3):e249.10.1038/nutd.2016.55 59 MastroberardinoLSpindlerBPfeifferRSkellyPJLoffingJShoemakerCBet alAmino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family

The varied expression of influx/efflux transporters (e.g., ABCB1/P-gp) [44], divergent pro-survival signaling, apoptosis pathways or DNA repair capacity [45], as well as the expression profile of non-coding RNAs [46] and epigenetic regulatory factors [47] may cause the different IC50 values of APS

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