p21 and glutathione Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis Need us to run inhibitor screens or profile your compounds against Dcaf11 The P53–P21–RB1 pathway promotes BRD4
Description
Selenium deficiency during pregnancy leads to reduced placental weight and reduced fetal blood glucose levels in mice (Hofstee et al., 2019), likely due to deficiencies in SELENOP and SELENON

Belfiore R, Rodin A, Ferreira E, Velazquez R, Branca C, Caccamo A, et al
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Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia

[DOI] [PubMed] [Google Scholar] 33.Mattsson P, Medvedev A
