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In hypogonadism, OS impacts steroidogenesis, primarily affecting Leydig cells and mitochondrial functions [163]
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Moreover, the IN codelivery of berberine and evodiamine by selfassembled thermosensitive hydrogels, showed good release properties and achieved antidepressant effects by regulating monoamine neurotransmitter metabolism and related metabolic pathways, providing a noninvasive treatment strategy for the clinical treatment of depression [407]
Pitts,RF.1975Production of CO2 by the intact functioning kidney of the dog Med Clin N Am59507517 32
Battie MC, Videman T
