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Rodent subjects were split into two groups: Young-adult male mice that were either genetically unable to use B12 properly or fed a B12-deficient diet for seven weeks

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Glutamine and Glutamate: Important Compounds for Immunity and Cell Proliferation. Brazilian Journal of Medical and Biological Research 36(12): 153950

Entacapone is a reversible inhibitor of COMT, while tolcapone is a reversible inhibitor of both COMT and another enzyme called COMT-B
