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Any statements about in-use shelf life are therefore illustrative only and cannot be relied upon as clinical guidance

doi:10.1093/jn/138.1.130 Tutelyan VA, Makhova AA, Pogozheva AV, Shikh EV, Elizarova EV, Khotimchenko SA

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**Common side effects** of Botox include neck pain, muscle weakness, and slight bruising at the injection sites

The inhibitory effects of chronic exposure of vitamin B12 on glutamate-induced neurotoxicity were determined in cell culture, probably by altering the membrane properties through S-adenosylmethionine (SAM)-mediated methylation [26, 27]