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The protein precipitate was removed by centrifugation at 3000 g for 5 min and aliquots were analysed for cysteine-bimane adducts by HPLC

[DOI] [PubMed] [Google Scholar] Calvert P, Yao KS, Hamilton TC, O'Dwyer PJ

2 , 10 However, the gastrointestinal adverse effects associated with oral therapy are a substantial disadvantage, notably if this results in a longer time for drug absorption and hence a longer time to reach therapeutic effect

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Collectively, these advantages highlight the significant potential of liposomes to improve the therapeutic index of drugs, enhance treatment efficacy, and provide safer alternatives in clinical practice (Kim and Jeong 2021