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There is already a plethora of evidence suggesting that aldehydes generated by lipid peroxidation are involved in ASD

Histologically, they will show vascular changes such as intimal hyperplasia, variable vessel fibrosis and disruption of elastic laminae in arterial walls (2)

Jung S-A, Lee D-H, Moon J-H, Hong S-W, Shin J-S, Hwang IY, et al

Therefore, therapeutic strategies aimed at modulating iron homeostasis, enhancing antioxidant defenses, preserving mitochondrial integrity, and inhibiting lipid peroxidation hold great promise for suppressing ferroptosis and mitigating the progression of tissue fibrosis and other pathological conditions