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Upregulated genes were enriched in pathways related to T cell differentiation and activation (for example, RUNX3 , IFNG , TNFSF9 ), negative regulation of the immune response (for example, WASL , ID2 , TNFAIP3 ) and circadian regulation of gene expression (for example, RORA , PER1 , NRIP1 ) (Fig

doi: 10.3389/fnins.2021.678154 [DOI] [PMC free article] [PubMed] [Google Scholar] 12
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A clinical trial published in Evidence-Based Complementary and Alternative Medicine found that infertile men taking ashwagandha for three months showed significant improvements in all sperm parameters, with 14% of participants achieving pregnancy with their partners during the study period
