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Using genetic engineering, dendritic cells (DCs) have been engineered to secrete exosomes expressing Lamp2, an exosomal membrane protein, fused with the neuron-specific RVG peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) 35

It serves as a cofactor for more than 150 enzymes in the body, including the metabolism of homocysteine and tryptophan

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10.1186/s11658-020-00205-0 Cell Mol

Diagnoses were made through a combination of clinical assessments and histological analyses, with none of the patients having received any systemic or topical treatments for a minimum of 2 weeks prior to the biopsy