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Accessed 12 Oct 2015

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Plasma samples were diluted with three volumes of ethanol containing 1% formic acid, and the resultant supernatant was subjected to online sample clean-up by turbulent flow chromatography on a Cyclone (50 0.5 mm) column from Thermo Fisher prior to LCMS analysis

Cyanocobalamin vs Hydroxocobalamin Hydroxocobalamin is another naturally occurring form of B12 produced by bacteria in the digestive tract during the breakdown of foods

Notably, the adverse effects caused by metformin therapy for adolescent patients with PCOS, especially gastrointestinal side effects, need to be a concern, as they may affect their quality of life and treatment adherence