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In some cases, fibrosis (the formation of scar tissue) or the accumulation of fluid can contribute to these lumps

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These are (in order of reaction), -ketoacyl-ACP synthase (contained in a domain composed of amino acids 2404), -ketoacyl-ACP reductase (contained in a domain composed of amino acids 18762112), 3-hydroxyacyl-ACP dehydratase (contained in a domain composed of amino acids 8741106) and enoyl-CoA reductase (contained in a domain composed of amino acids 15641854)

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