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Although nanotherapy has many advantages, some problems remain: the complexity and heterogeneity of tumor biology lead to uncertainty about its efficacy, as the interaction of NPs with this biology is not yet clear, and challenges related to NP cost, chemical processes, manufacture, and control persist (172, 173)

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EMA401: an old antagonist of the AT2R for a new indication in neuropathic pain

In vivo anti-melanogenesis activity and in vitro skin permeability of niacinamide-loaded flexible liposomes (Bounsphere)