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Description
Further, MTX increased the expression of PERK (Figure 6B), GRP78 (Figure 6C), ATF4 (Figure 6D), and CHOP-10 (Figure 6E) in the liver compared to CTRL, indicating that ER stress is implicated in MTX-induced hepatotoxicity
Bacteriostatic Water for Injection is a sterile, non-pyrogenic solution of water containing 0.9% benzyl alcohol as a preservative
It requires no injection, has excellent safety data, and is widely available

R.KolangikhahM.AsadpourE.ForouzanfarF.HosseinzadehH

PMID: 18644977