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In this context, mitochondria, which are primarily used to maintain energy homeostasis and support balanced biosynthesis in normal cells, become central organelles for fulfilling the heightened biosynthetic and energetic demands of proliferating cancer cells

The N, N-Di(2-hydroxybenzyl) ethylenediamine-N, N-diacetic acid monohydrochloride (HBED), an iron chelator, mitigates iron-related damage by binding ferrous ions, facilitating their transport across BBB, and converting them to ferric ions

By contrast, another subtype of renal cell carcinoma (chromophobe) contains the lowest GGT1 expression levels among tumours

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[DOI] [PubMed] [Google Scholar] 153.Vazquez Roque MI, Camilleri M, Stephens DA, et al