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While the ATP generating capacity of glutaminolysis is considered to be redundant with glucose oxidation and/or FAO, the oxidation of glutamine is indispensable for driving T cell proliferation and differentiation (102)

doi: 10.2337/diacare.28.5.1083

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Collectively, DNA methylation precisely controls key gene expression, significantly affecting macrophage polarization and inflammatory responses, making it a potential epigenetic therapeutic target in diseases such as atherosclerosis

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