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Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia

At present, in view of extensive research on key mechanisms and regulators of ferroptosis, a large number of small molecule drugs have been found to induce or inhibit ferroptosis to alleviate renal tissue injury in various kidney diseases, such as RSL3, erastin, Fer-1, vitamin K and quercetin

The 7% incidence rate was consistent across dose groups, though higher doses trended toward higher rates

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