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We identified several mutated nrf2a alleles harboring insertion, deletion, or a mix of both and selected an allele presenting a deletion of 5 nucleotides between the nucleotides 1450 and 1454 of the reference coding sequence, this deletion is in the exon 5 before the DNA binding domain of the nrf2a protein (hereafter referenced as nrf2a5 ) (Fig 1A)

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Mol Endocrinol 27(3):511523 Donadeu FX, Ascoli M (2005) The differential effects of the gonadotropin receptors on aromatase expression in primary cultures of immature rat granulosa cells are highly dependent on the density of receptors expressed and the activation of the inositol phosphate cascade

In particular, the 7 nicotinic receptor plays a significant role in regulating neuroinflammation in astrocytes and microglia

Similar to bacteria, fungi employ the amino acids found in their cell walls for capping and stabilizing the cell walls