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Figure 1 The biological effects of testosterone are mediated both by direct binding and activation of the androgen receptor, as well as indirectly through its metabolic conversion to biologically active derivatives, including 5-dihydrotestosterone (DHT) via 5-reductase and oestradiol via aromatization, which subsequently act through androgen and oestrogen receptors (ER/ER), respectively

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FIGURE 2 This oxidative stress environment can activate immune signalling pathways promoting neuroinflammation through mitochondrial dysfunction and impaired mitophagy, as observed in recent studies on ASD brains (Pinto Payares et al., 2024)

Glutathione and Protein, Amino Acids Because amino acids are the precursors of glutathione, and glutathione itself is comprised of three of them (cysteine, glutamic acid and glycine), the amount of protein one consumes logically influences our natural glutathione production

This plant has gained medical and socioeconomic popularity because it has shown great health benefit and it is easy to cultivate (Zhu et al., 2020)