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Testing and dietary management are important for those affected

This 15-amino-acid peptide, derived from a protective compound naturally found in gastric juice, has been the subject of hundreds of preclinical studies examining its potential effects on tissue repair, gut health, and neuroprotection

The effective elimination half-life of setmelanotide is approximately 11 h, and the estimated total apparent steady-state clearance following subcutaneous administration of setmelanotide at a daily dose of 3 mg is 4.86 L/h, as determined by the population pharmacokinetic model [153]

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