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Description
No other single research peptide has as extensive a preclinical record specifically in the gastrointestinal context

X.FuJ.MaS

doi: 10.4161/cbt.7.12.7067 237 SosaVMolinTSomozaRPaciucciRKondohHMELL

The ground-breaking finding that mice expressing dominant-negative N-cadherin, an adherent junction protein, develop spontaneous (not induced using chemicals or infections known to induce colitis in mice) inflammation in the gut epithelium further supports the key role of cell-to-cell adhesion, especially in its capacity to contribute to overall mucosal barrier function in regulating mucosal immune homeostasis
Most of the research began in rodents, and much of the practical experience comes from human clinical use
