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Therefore, using Riluzole to target and block glutamate transport, in combination with chemotherapy and immunotherapy, has become a promising clinical research direction for overcoming resistance [227]

Exposure to environmental factors or mutations in PD-associated genes of patients with either sporadic or familial PD may cause mitochondrial dysfunction that ultimately results in PD

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This mechanism has been studied in clinical trials investigating hyperpigmentation and photoprotection, making it a frequently used compound in dermatological and cosmeceutical research protocols