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The tumor stroma elevates the expression of proteases such as plasminogen activation system and matriptase that are involved in the activation of pro-HGF

This receptor is widely expressed in the reproductive system and other tissues and involved in various physiological processes, including reproduction, metabolism, and neuroprotection [139]

The antioxidants (present in fruits, vegetables, and nuts) help to repair cells, have anti-inflammatory properties, and reduce excessive free radical formation in the body, which is the main mechanism of action of cancer cells
If persistent, dose adjustment usually addresses it

In the PNI, MSCs secrete trophic factors that are important for the remodeling and regeneration of the tissue