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Rather, a summary of the types of organic compounds listed by Chasseaud is provided as representative of electrophilic xenobiotics that generate mercapturates when administered to experimental animals (rabbits and rats have been most extensively tested): halogenated benzenes, halogenated nitrobenzenes, other arylnitro compounds, chloro- S -triazines (herbicides), phenoltetrabromophthaleins, aralkyl halides, alkyl and alicyclic halides, sulfates and nitro compounds, allyl compounds, alkyl methanesulfonates, organophosphorus compounds, polycyclic aromatic hydrocarbons (via arene oxides), various ,-unsaturated compounds (esters, aldehydes, ketones, lactones, nitriles, nitro compounds, and sulfones), arylamines, arylhydroxylamines, carbamates, and related compounds

2017;12:e0186374

The BioGRID interaction database: 2019 update

Apoptosis inducing factor acts as a suvival factor in acute myelogenous leukemia through mitochondrial complex 1

expression in reactive astrocytes correlates with increased cell death related DNA damage in the hippocampus and entorhinal cortex in Alzheimer's disease Exp