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When induced to develop EAE, these mice showed a substantial reduction in disease severity, which was not further affected through additional FTY720 treatment, suggesting that the main effect of FTY720 in EAE involves modulation of astrocyte function but not the arrest of lymphocytes in lymph nodes (178)

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Importantly, there was no classic sedationsubjects maintained normal alertness when awake

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-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo

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Folate-targeted nanoparticles for glutamine metabolism inhibition enhance anti-tumor immunity and suppress tumor growth in ovarian cancer

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Kohzuma K, Froehlich JE, Davis GA et al (2017) The role of lightdark regulation of the chloroplast ATP synthase

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