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These gases diffuse into the bloodstream, travel to the lungs, and are exhaled

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Major modifications for 2026 As outlined in the 2026 Summary of Major Modifications and Explanatory Notes, the major modifications for 2026 include the following: Further examples or clarifications have been added to the following substance classes to help athletes and their entourage better identify prohibited substances: S1

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Clinical trial data from the SURMOUNT-1 study showed that gastrointestinal adverse events were significantly more common during dose escalation periods (Jastreboff et al., 2022, NEJM)
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