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Globally, I believe [no current data to support this] that large doses of oral B12 have been used to some good effect, although it's not possible to work out who will benefit unless you do the experiment, and for that, if it meets the criteria of a clinical study, it needs [certainly in the UK] to be appropriately designed and reviewed before the work starts, and the results should be presented afterwards

education and demonstrating clear benefits will help

When progress has stalled despite rest or rehab

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