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5a) and Epstein in 1966.49 In the words of this last author: The ability of the kidneys to excrete a concentrated urine is impaired together with other renal functions whenever the kidneys are progressively scarred and the amount of functioning renal parenchyma is diminished

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(1) Preparation of canaglitide peptide resin Take 1.5mmol of the first protective amino acid and 1.5mmol HOBT, dissolve it with an appropriate amount of DMF and cool to 0~15C

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History of B-12 as a treatment for pernicious anemia B-12 deficiency is the cause of pernicious anemia, a usually-fatal disease of unknown etiology when it was first described in medicine