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The STEP trials also showed that weight loss continued throughout most of the treatment period, with most participants still losing weight at 68 weeks
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Disulfides serve as (largely permanent) molecular staples that direct and stabilize the three-dimensional structure of proteins, and determine the distance and angle constraints between the joined cysteine residues, therefore stabilizing the folded state with respect to the unfolded form 2
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doi: 10.1016/j.ijpharm.2022.122123
