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This finding was particularly notable because it occurred despite significant fat loss, demonstrating that the peptides lipolytic effects do not compromise metabolic health

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Dehydration is caused by not drinking enough fluid as well as by increased loss of fluid from sweating, diuretics, vomiting, and diarrhea

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CNS copper uptake is regulated via the high affinity copper uptake protein 1 (CTR1) whereas copper release from cells is regulated by two copper-transporting P-type ATPases (ATP7A and ATP7B) [188]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 129

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So far, the overall response of these patients to Amivantamab is 33% (50% in patients with no previous lines of therapy, 46% in patients with no prior c-MET inhibitor, and 21% in patients with prior c-MET inhibitor therapy)

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