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Thus, TB-500 may be hypothesized to support angiogenesis by combining a cytoskeleton-linked increase in endothelial motility with signaling changes that raise pro-angiogenic programs (VEGF-A and Ang2/Tie2) via Notch/NF-B coupling in damaged cellular structure

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BPC 157 induced Achilles tendon-to-bone healing: tendon to bone could not be healed spontaneously, but it was recovered by this peptide [19,22]