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1 April 2011

Better Absorption for Some Individuals: People with certain medical conditions, such as pernicious anemia or gastrointestinal disorders like Crohns disease, might not absorb enough vitamin B12 from food

The recommended dietary allowance for adults is 2.4 micrograms per day according to the NIH Office of Dietary Supplements (updated 2025)

In addition to oligonucleotide therapeutics, some small-molecule NNMT inhibitors have been reported recently [5659] and several have shown effectiveness in the prevention or treatment of obesity and T2D in vitro [60, 61] or in preclinical animal models [10, 58, 62], validating NNMT as a pharmacological drug target

So, a 1 mg dose of B12 is the same as 1000 mcg