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There was no significant difference between the weights of the animals at the beginning of the experiment

High-fidelity drug-induced liver injury screen using human pluripotent stem cell-derived organoids

A.HasanuzzamanM.GillR.TrivediD

10.1002/hep.24563 343 YangZ.MingX

Sulfamethoxazole and trimethoprim is contraindicated in the following situations: known hypersensitivity to trimethoprim or sulfonamides history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides documented megaloblastic anemia due to folate deficiency pediatric patients less than 2 months of age marked hepatic damage severe renal insufficiency when renal function status cannot be monitored concomitant administration with dofetilide (see PRECAUTIONS)