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Gonzlez et al., 2019a,b)

Hashimoto's thyroiditis and autoimmune thyroid conditions Hashimoto's thyroiditis is the most common autoimmune disease, involving immune attack against the thyroid gland that progressively destroys its ability to produce thyroid hormones

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Metformin, an AMPK activator, would have much better therapeutic outcomes when given to stroke patients exhibiting reduced brain AMPK activity (Jia et al., 2015)
