glutathione bromopyruvic acid conjugate Glutathione-mediated conjugation of anticancer drugs: an overview of reaction mechanisms and biological significance for drug de Conjugation With Glutathione and Mercapturic
Description
As oxidative stress levels rise, irons catalytic cycle is altered, inhibiting DNA demethylases of the Ten Eleven Translocation (TET) family and raising DNA methylation levels (Franco et al., 2008)
10.1111/j.1471-4159.2009.06172.x 236 SilvaM
Apart from being produced through the exchange of cystine and glutamate, it can also be obtained via the transsulfur pathway (TSP)
Alvarez XA 1 , Laredo M, Corzo D, Fernndez-Novoa L, Mouzo R, Perea JE, Daniele D, Cacabelos R
(2023) 186:50845097 e5018
