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doi: 10.1002/ijc.24582
Sex Med Rev (2015) 3(1):1123
10.1007/s13311-020-00968-6 139 SantocchiE.GuiducciL
Similar content being viewed by others Introduction Fumarate hydratase (FH) mediates the reversible conversion of fumarate to malate in the tricarboxylic acid (TCA) cycle
For example, in recurrent colorectal cancer, metastatic outgrowth is driven by Lgr5 + stem cells directly or by Lgr5 + cells that have transformed from Lgr5 non-stem cells via phenotypic conversion 10,11
