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TMAO serves as a prognostic marker for survival in CKD patients, correlating with glomerular filtration rate, C-reactive protein, and cystatin C (137)

The vital role of DA in neuroinflammation was also evidenced by the observation that excessive DA released into the synaptic cleft may stimulate regional microglia directly and trigger a neurotoxic signal cascade (Thomas et al., 2008)

The same dose of L-carnitine and selenium was used in the intervention group of this trial, while participants in both the intervention and control groups also received standard therapy (methimazole and beta blockers)