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AIF is a protein located within the mitochondria, whose activation leads to a caspase-independent pathway of apoptosis by mediating DNA fragmentation and chromatin condensation [49]
Their findings revealed that surface-modified functional groups on Ag 2 Se NPs, including octadecanethiol (ODT) and 11-mercaptoundecanoic acid (MUA), played a crucial role in the efficient extraction of peptides and proteins, providing an effective method for biological sample analysis

doi: 10.1074/jbc.M311096200

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However, glutathione reductase reduces GSSG via a NADPH-dependent mechanism, to keep the intracellular concentration of GSSG at extremely low concentrations [229]
