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Recommendations vary widely and there is no clear consensus

Cys are the elements most sensitive to fluctuations of the cellular redox environment, undergoing different types of chemical modifications in response to such variations

Protein precipitation was performed by adding 10 volumes of 25% MeOH in acetonitrile (ACN), except for the brain homogenate which was extracted in 100% MeOH

Thereby, sensors can, for example, document the amount and quality of sleep and therefore provide insight into a concomitant factor contributing to fatigue as a PRO cannot assess precisely the scope of this type of disturbances (Bradshaw et al., 2022)

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