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705 Albiflorin not only inhibits neuronal ferroptosis by reducing the levels of lipid peroxide and iron and regulating ferroptosis-related proteins, but also inhibits microglia activation and reduces the production of pro-inflammatory cytokines, thereby promoting motor function recovery after SCI in rats

This effect is achieved by increasing HO-1 activity and signaling to biliverdin reductase (BVR)

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Wu Y., Li Q., Zhang R., Dai X., Chen W., Xing D

Pagels N

(2000) Substrate recognition by P-glycoprotein and the multidrug resistance-associated protein MRP1: a comparison