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10.1016/j.tifs.2017.02.002 Trends Food Sci

Da Costa LouzadaMLDos Santos CostaCSouzaTNDa CruzGLLevyRBMonteiroCA

Theorized to involve downregulation of glucocorticoid receptors and reduced responsiveness of target cells, intermittent use or rotation of corticosteroids may help mitigate potential tolerance [83]

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For instance, earlier research had hinted at a connection between maternal metabolic extremes (very high folate/B 12 ) and autism, but it was unclear how this dovetailed with the well-established risks of deficiency [16]
