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et al., Genome Res 10, 333-343 (2000)

As discussed above, glutamine is imported by the transporter SLC1A5, while leucine is taken up through the bidirectional antiporter SLC7A5 which exports glutamine out of the cell

The end of each chain threads its way up into the middle of the neighboring subunit in the opposite ring--notice how the subunit colored red is poking up into the blue subunit

Bertino J, Carman M, Weiner H, Cashmore A, Moroson B, Srimatkandada S, et al

Studies have shown that IL-2 exerts anti-inflammatory effects and maintains immune tolerance by regulating the balance of Th17/Treg and Tfh/Tfr, and is a potential treatment for RA (Wu et al., 2020)