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277 The Ca 2+ -independent pathway is mediated through the activation of RhoA and the stimulation of Rho kinase, which phosphorylates and inactivates the myosin light chain phosphatase target subunit

The right choice depends on deficiency cause, route preference, tolerability, availability, and monitoring needs

Some compounded formulations match or approach this stability, while others may degrade somewhat faster due to different excipients or preservative concentrations

and Olorofim (F901318), a broad-spectrum antifungal agent with fungal-specific inhibition (Maertens et al., 2025)

(PubMed) Mangiapane E, Pessione A, Pessione E