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The Wnt agonists and antagonists from the DP predominantly act on matrix cells despite their autocrine potential To explore the proposition that Wnt signaling activity in the bulb is normally reduced during late anagen, the Axin2-lacZ Wnt-reporter allele 35 was introduced in both control and dMF1/2 mutant mice

Introduction Despite considerable technological developments and continuous research to find and implement an effective and safe drug, there are still none that have positive therapeutic effects, target multiple disease entities, and, at the same time, have no side effects