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Subclinical hepatic encephalopathy impairs daily functioning

Elevated histone acetylation was confirmed in an additional cell line and shown to decrease through the depletion of KG or the suppression of KGDDs using knockdown or inhibition of IDH1, glutamine starvation or succinate supplementation (Fig

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l-carnitine administration (6 g/day for 4 weeks) led to a decreased ROS and increased glutathione peroxidase level, but not to a significant extent