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Additionally, overexpression of USP20 wild type or USP20 S333A (phosphorylation-impaired mutant) blocks the localization of internalized 2 AR in autophagic vesicles, whereas a USP20 S333D (phosphorylation-mimetic mutant) has no effect

Eur J Clin Microbiol Infect Dis

Instead, it's a broad term for a collection of disorders that prevent the small intestine from properly absorbing nutrients from your food

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