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Conditional depletion of HGF in CAFs resulted in decreased development of liver cancer, and depletion of the HGF receptor MET in hepatocytes or tumour compartments reduced tumour growth [230]

IGF-1 LR3 is a peptide involved in growth hormone production

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Although it has been proposed as an effective biomarker, only EoPE (but not LoPE) is associated with increased PAI-1/PAI-2 ratio [75]
