chloroquine glutathione synthase Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy Glutathione Synthetase - an overview

To further explore how the ferroptotic pathway is affected by the progression of the pathology, we performed proteomic analysis on the neuronal progenitor cells (NPCs) differentiated from iPSC of PSEN1-9 (depicted as AD-NPCs) and isogenic controls

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Scalabrino G

Endocrine Reviews 26, 465478, 10.1210/Er.2004-0027 (2005)

Such oxidations are in direct competition with glutathione reductase and ABC transporters which usually maintain very low GSSG concentrations under physiological conditions 5,7,62,63,64

There are small clinical and post-procedure studies and multiple reviews