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Risk factors of CAD development including smoking, blood pressure, obesity, and cholesterol can also vary among different ethnicity groups [184, 185], resulting in certain groups having an earlier onset and worse outcomes of CAD

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While this trial showed trends toward fat loss in the treatment groups, the primary endpoint of statistically significant weight reduction compared to placebo was not consistently achieved across all dose groups, and effect sizes were more modest than hoped

This review underscores the need for continued exploration and optimization of CAR-T strategies to address the unmet needs of SLE patients

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