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2 However, the same biological activity that makes peptides interesting also creates risk

6.6.2.2 Synergistic attribution of the triple-defense mechanism The triple-defense mechanism illustrated in Figure 7 represents synergistic actions of both parent compounds and gut microbiota-derived metabolites, rather than singular attribution

Finally, recent studies have suggested that the oxidation of lipids (such as polyunsaturated fatty acids and cholesterol) generates electrophilic compounds that modify Lys residues in SOD1, inducing its aggregation (Dantas et al., 2020)

It is extensively studied in molecular and regenerative research for its role in cellular signalling, tissue organisation, and biological repair pathways

SIRT3 as a potential therapeutic target for heart failure