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The primary endpoint was a minimum of 50% reduction in tumor cell count assessed by quantitative multiplex immunofluorescence (qmIF) within the tumor bed of the surgical tissue (post-treatment) compared to the biopsy tissue (pre-treatment)

Neuropsychopharmacology 38:241242

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This process is highly efficient in rodent models, in which complete remyelination occurs within weeks or months following the experimental insult

however, in patients with non-pulsatile bilateral tinnitus, with or without symmetric hearing loss, and an otherwise normal history and physical exam, imaging is not necessary